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Use of systemic corticosteroids in the treatment of acute gouty arthritis : what is the evidence? Rev Port Med Geral Fam [online]. ISSN Aim: To evaluate the efficacy and safety of systemic corticosteroids SC in the treatment of acute gouty arthritis AGA and its benefits to classic treatment namely colchicine and nonsteroidal anti-inflammatory drugs NSAIDs.
Review methods: Clinical guidelines NOC , systematic reviews RS , randomized controlled trials RCT and meta-analyses MA , published between June and June , using the MeSH terms glucocorticoids, gout suppressants, adrenal cortex hormones, acute disease, gout, and hyperuricemia.
If on the one hand, some studies mention a more significant improvement of the symptoms with the use of SC, especially in the first days of treatment, on the other hand, they mention them as effective as the classic treatment.
Thus, the choice of agent for AGA treatment should be determined based on the patient's profile. Servicios Personalizados Revista. Similares en SciELO. Palabras clave : Gout; Glucocorticoids.
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Directory of Open Access Journals Sweden. Arthritis in our midst. This study aims at highlighting the importance of the emergence of new therapies in order to attenuate the progression of rheumatoid arthritis, and to analyze risk-benefit offered by their treatment and assess the feasibility and cost of the same. Accelerated nodulosis is the development of a large number of nodules during a short time in adult patients presenting either seropositive or seronegative rheumatoid arthritis. These nodules are usually described as associated to methotrexate therapy. There have been three case reports of patients who developed peripheral accelerated nodulosis while receiving leflunomide. We describe a years old woman with seropositive rheumatoid arthritis who developed accelerated nodulosis after four months receiving leflunomide therapy.
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